Nfl 2025 Opening Day. The nfl will play a regular season game in madrid, spain in 2025, as the nfl prioritizes global growth and expands the international games to new cities and markets. The nfl future opponents are based on the nfl's scheduling rotation.
Pirates pitching phenom paul skenes could make his first opening day start, with the bucs set to begin the 2025 season in miami. The official start of the 2025 nfl league year is march 12 at 4:00 pm/et.